The effectiveness of the char plant (Solenostemon Leaves) in improving lipid and kidney function in rats suffering from oxidative stress

Abstract

It is now widely accepted that oxidative stress & lifestyle-associated illnesses are closely related. Oxidative stress is defined as an imbalance among the production of reactive oxygen species, also known as free radicals, and the defenses that are given by antioxidants. this research aims to determine the efficacy of the char plant (Solenostemon Leaves) in improving lipid profile, kidney function, & antioxidant enzymes in rats suffering from oxidative stress. The investigation was conducted within an animal home. Before beginning the experiment, all mice were provided with a basal diet for one week. They were then separated into two primary groups. The first group, consisting of six rats, served as the control negative (C-ve) normal rats & was only fed the basal diet for an interval of twenty-eight days. The second main group received a solitary intraperitoneal dosage of potassium bromate& was then separated into four groups. Three of these groups were provided with char plants at varying concentrations (5%, 10%, and 15%), while one group served as a control and was infected with the disease but didn't eat the experimental diet. The findings indicated that G3 (a five percent char plant) exhibited the most significant reduction in serum triglyceride (TG) levels (milligrams per deciliter), while all mice fed experimental diets (G4, G3, and G5) demonstrated significant reductions in serum creatinine. Also, Group 5 (15% char plant) revealed a higher increase in SOD activity compared with the control (+) group. The research recommends adding leaves of the char plant to diets at certain concentrations to improve biological functions (lipid profile and kidney function).