A Simple Synthetic Strategy For The Synthesis Of Benzoxepinopyrrolidines Under Microwave Condition

Authors

  • A. Senthil, S. Nandhakumar, A.R.N. Vashinavi, Kalpana Umapathy, M. Shyamala Bharathy, K. Sukanthi, Sivakumar.N* Author

Keywords:

Baylis-Hillman reaction, Benzoxepine, allyl alcohol, cyclization, nitroolefin, [3+2] azomethine,

Abstract

Simplemethod synthesis of 2-benzoxepines starting material from (E)-2-nitro-3-arylprop-2-en-1-ols with paraformaldehyde. Furthermore, the 1,3-dipolar cycloaddition of 2-benzoxepines with azomethineylides using paraformaldehyde led to the formation of tricyclic benzoxepinopyrrolidine architectures for the first timeunder microwave condition process

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Published

2025-11-15