Impact on ovarian reserve (AMH) in women of childbearing potential with endometrioma undergoing ovarian sclerotherapy versus laparoscopic cystectomy

Abstract

Endometriosis is a pathology that has a great impact on patients with fertility problems and its management continues to be highly debated, there are different types of treatment (observation, medical or surgical treatment and assisted reproduction techniques). A systematic review with meta-analysis of the 10-year-old literature related to sclerotherapy of ovarian endometrioma, laparoscopic cystectomy of ovarian endometrioma, anti-Müllerian hormone and ovarian reserve is carried out. We are left with 5 studies that evaluate the values of anti-Müllerian hormone before and after intervention, finding a low heterogeneity index when evaluating the 5 articles with RevMan 5.0.0. But their results are not statistically significant. We worked with 170 and 186 events (sclerotherapy and laparoscopic cystectomy, respectively). In this study, no statistically significant differences were found between the two procedures in terms of the impact on the ovarian reserve (anti-Müllerian hormone). However, it should be noted that of the 5 articles, only 3 of them had a lower impact on the values of anti-Müllerian hormone in relation to ovarian sclerotherapy. It is concluded that ovarian sclerotherapy is a very good alternative for endometrioma management without major impact on the ovarian reserve.