Optimizing Pharmacotherapy in Older Adults: Emerging Strategies to Reduce Polypharmacy-Related Risks
Keywords:
polypharmacy, DE prescribing, geriatrics, medication therapy management, Beers Criteria, older adults, adverse drug events.Abstract
Background: the use of five or more medications simultaneously is very common among older adults and is generally considered a major risk factor for adverse drug events hospitalizations and mortality. prescribing efforts of Standard DE have relatively limited success in facilitating clinicians in addressing inappropriate medication use
Objective: To scope of the polypharmacy problem and synthesize emerging evidence-based strategies for optimizing pharmacotherapy in the elderly by medication reduction to a more framework of medication appropriateness.
Methods: A literature from 2020 to 2023 from the databases including PubMed, Scopus, and Cochrane focused on clinical trials systematic reviews Emerging strategies of the Age-Friendly Health Systems "4Ms" framework implementation of clinical decision support systems with explicit criteria as the Beers Criteria of the guides for Geriatric Pharmacotherapy and DE prescribing and team-based care
Conclusion: Multidimensional proactive process. Integration of structured frameworks technological tools and evidence-based guides with interdisciplinary collaboration will lead to significant reductions in risk related to polypharmacy ultimately resulting in better outcomes for the elderly which.
