Role of Glycemic Control in Modulating Coronary Inflammation and Plaque Vulnerability in Low-Risk ACS: A Coronary CT-Based FAI Study
Keywords:
Diabetes Mellitus (DM), Low-Risk ACS, Coronary Computed Tomography Angiography (CCTA), Pericoronary Fat Attenuation Index (FAI) ,C-Reactive Protein (CRP).Abstract
Diabetes mellitus is a well-established risk factor for the development and progression of coronary artery disease.Coronary artery disease (CAD) remains a major contributor to cardiovascular morbidity and mortality. Therefore, early identification of low-grade vascular inflammation is essential for risk stratification and prevention of adverse events. Coronary computed tomography angiography (CCTA), when combined with pericoronary fat attenuation index (FAI) analysis, provides a non-invasive imaging modality to detect coronary inflammation and characterize high-risk atherosclerotic plaque features. alongside systemic inflammation assessed via C-reactive protein (CRP) levels. This investigation focuses on patients with low-risk acute coronary syndrome (ACS) who have been known to be diabetic.
