Analyzing the Mimics: A Comprehensive Examination of Cryptosporidium parvum Differential Diagnosis

Abstract

Cryptosporidium parvum is a pathogen that can lead to severe gastrointestinal disease, especially in neonates or individuals with weakened immune systems. It could kill you. Cryptosporidium parvum necessitates a minimal quantity of the pathogen to initiate infection and excretes a significant amount of it. The goal of this systematic review is to look at the many tests used to tell the difference between Cryptosporidium parvum and other diseases.

Method To make search strings, you need to use relevant keywords and phrases. Choosing a database requires a multidisciplinary approach that makes use of resources like PubMed, Google Scholar, Cochrane Library, Embase, and Web of Science. The collection and processing of data entail the evaluation of fetal samples and the comparative analysis of diagnostic performance, sensitivity, and specificity through statistical methodologies. It involved human studies with individuals suffering from diarrheal diseases and compromised immune systems, employing diverse diagnostic techniques including PCR. Samples were obtained from various geographic areas to guarantee a comprehensive representation of Cryptosporidium infections. We used PCR, ELISA, and microscopy to figure out the differential diagnosis. Data was gathered based on things like the size of the sample, the diagnostic methods used, the results, and the identification of Cryptosporidium parvum subtypes or species.

Results Results revealed that C. parvum can be diagnosed either microscopically or by immunochemistry techniques. While using molecular methods are usually being used for detecting specific strains of C. parvum and not for differential diagnosis.

Conclusion The transmission of Cryptosporidium parvum, a particular strain of Cryptosporidium, into the gastrointestinal tract and the subsequent development of cryptosporidiosis has been the subject of extensive scientific research...