Pharmaceutical Delivery Methods Using Nanotechnology: Current Trends and Prospects

Abstract

With many benefits over traditional synthetic nanocarriers, including biocompatibility, biodegradability, and decreased toxicity, bio-based nanomaterials have become a game-changing platform in drug delivery systems. This study thoroughly examines the current state of biobased nanomaterial synthesis, functionalization, and application. This study examines lipid-based carriers, dendrimers, proteins, and metallic nanoparticles that are synthesized using green chemistry to enhance regulated and targeted medication delivery. Combination treatments that make use of biobased nanocarriers tackle problems like multidrug resistance, and advances in surface modification techniques and stimuli-responsive designs have increased the efficacy and site-specific release of drugs. Pulmonary and personalized medicine applications exemplify their adaptability in accomplishing localized delivery and customizing treatments to unique patient profiles. Despite challenges in large-scale production, stability, and regulatory approval, biobased nanomaterials have the potential to revolutionize medicine delivery. Advancements in green synthesis, multifunctionality, and nanocarrier optimization are driving this revolution. Better clinical outcomes and a long-term strategy for precision medicine are possible with their incorporation into next-gene medicines. To address the pressing demand for safer and more sustainable drug delivery platforms in modern medicine, this review highlights the eco-friendly, biocompatible, and biodegradable nature of bio-based nanomaterials.