Effect of freshwater algae on improving liver function in rats injected with carbon tetrachloride

Abstract

The term "algae" is not a phylogenetic one, but rather refers to a broad category of economically important creatures. A group of major creatures with varied ancestries, evolutionary histories, and biochemistry, algae are not a phylogenetic notion. This experimental research intends to determine repercussions of various dosages of freshwater algae on enhancing liver function in rats injected with carbon tetrachloride, since many plant-derived chemicals are used as vital raw materials in the pharmaceutical sector. The rats were housed in a cage (animal facility) for a week before to the experiment. Two groups of rats were created, with the first group (n=6) receiving only food. A 28-day baseline diet was employed as a negative control group (C-ve). Rats were given Carbon Tetrachloride (n= 24), then given 5%, 10%, and 15% freshwater algae, and a control group that tested positive for the compound. A substantial difference was seen between the GPT activity levels of groups 2 and 5, and among groups 2 and 3 and 5 and the healthy rats group, suggesting that the GPT activity levels in group 5 were the optimal therapy. There were no discernible variations among the third and fourth group-fed rats. contrasted with the placebo group, group 5 (15% freshwater algae) had the highest values for serum (T.G.). Results show that freshwater algae has a beneficial impact on hepatic rats, with the rate of improvement rising in the 10% (freshwater algae) group due to its synergistic impact for liver tissue protection from toxicity by boosting antioxidant defence capabilities.