Laboratory Diagnosis of Coagulation Hemostasis in Chronic Hepatitis And Liver Cirrhosis With Hcv Etiology

Abstract

In HCV-associated chronic hepatitis blood coagulation system did not show significant changes before or during antiviral therapy. In HCV-associated liver cirrhosis activated partial thromboplastin time, prothrombin time, and thrombin time were prolonged, but showed improvement with AVT. Fibrinogen levels were significantly reduced by 2 times after 3 months of antiviral therapy. These findings suggest that antiviral therapy has a positive impact on coagulation parameters in liver cirrhosis.