Phase Characteristics of Changes in Autonomic Homeostasis in Children with Acute Intestinal Infections: A Case Study of Salmonellosis

Abstract

To date, numerous mechanisms of the pathogenesis of intestinal infections in children have been clarified based on the results of various studies. However, the role of reflex and humoral factors of the autonomic division of the central nervous system in the development of vegetative–visceral dysfunctions remains insufficiently understood. According to the theory of H. Selye and A.A. Koltypin, these dysfunctions have a phasic character and, regardless of etiology, are determined by the continuity in the functional activity of the leading mechanisms of autonomic support—sympathoadrenal, parasympathetic, and humoral. Comprehensive information on the state of autonomic homeostasis in a sick child can be obtained only by correlating clinical observations with biochemical and functional diagnostic methods. We found no publications containing such complex investigations in children with intestinal infections, particularly in patients with salmonellosis.