Frequency and Clinical Manifestations of Lacunar Strokes in Patients with COVID-19

Authors

  • Sevara Mukhamedkarimova, Murodbek Avezov, Nargiza Ergasheva, Ra’no Magzumova Author

DOI:

https://doi.org/10.64149/J.Ver.8.18s.394-407

Keywords:

: COVID-19; lacunar stroke; ischemic stroke; small vessel disease; neurological complications; post-COVID syndrome; neuroimaging; stroke epidemiology; risk factors; rehabilitation. Let me know if you'd like the abstract adapted for Scopus formatting or translated into another language.

Abstract

The present study investigates the frequency and clinical manifestations of lacunar strokes (LS) in patients with a history of COVID-19 infection. A total of 194 patients diagnosed with LS were examined, of whom 110 (56.7%) had previously contracted COVID-19, while 84 (43.3%) had not. Participants were stratified into two groups to assess the potential relationship between COVID-19 and lacunar stroke characteristics. Clinical evaluation included comprehensive neurological assessment, radiological diagnostics, and standardized rating scales for neurological and cognitive function. The findings revealed a higher proportion of lacunar strokes among COVID-19 patients, especially among males and individuals aged 18–44. COVID-19 patients with LS also demonstrated a higher prevalence of motor-sensory deficits, asthenic syndrome, and anxiety-depressive symptoms. Comparative analysis highlighted significant clinical and demographic differences between the COVID-positive and COVID-negative LS patients, indicating the potential influence of the viral infection on the pathophysiology and presentation of lacunar strokes. The study underscores the importance of timely neurological assessment in COVID-19 patients and the need for targeted rehabilitation and monitoring strategies.

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Published

2025-12-08

How to Cite

Frequency and Clinical Manifestations of Lacunar Strokes in Patients with COVID-19. (2025). Vascular and Endovascular Review, 8(18s), 394-407. https://doi.org/10.64149/J.Ver.8.18s.394-407